História da Guerra Santa, que ocorreu no século XVIII, 250 anos antes da série original de Saint Seiya. Se concentra na luta entre Tenma, um dos 88 santos que seguem Athena, e Alone, a reencarnação do deus Hades.

A boy whose friend died and became a ghost, starts high school. On his first day, a trunk is sent to him by his brother. From that moment on everyone are after him believing that he holds the mysterious powerful "Asura Machine".